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What is the LB.1 Variant? Everything You Need to Know

  • Post published:July 8, 2024
  • Post category:Blog

 

LB.1 variant

COVID-19 has kept the world on edge with its many twists and turns, and just when we think we have a handle on it, a new variant pops up. The latest on the radar is the LB.1 variant. What is it, and why should you care? Let’s dive into everything you need to know about this emerging variant.

What are Variants?

In simple terms, variants are versions of a virus that have undergone mutations. These mutations can change the virus’s behavior, including how it spreads, the severity of illness it causes, and its resistance to treatments or vaccines.

What is the LB.1 Variant?

The LB.1 variant is a new strain of COVID-19 identified by its unique genetic mutations, making it more transmissible than previous variants.

Is LB.1 more transmissible?

A characteristic of omicron subvariants is that they are very transmissible. LB.1 highly contagious, and it is spreading very readily.

Is LB.1 variant of COVID-19 more severe?

Although CDC has also presented any evidence suggesting that LB.1 might be more severe than its ancestors. However, a Japanese study claims that one of the mutations of LB.1 spreads faster than other variants.

The LB.1 strain, a mutation of the FLiRT group, was responsible for 17.5% of Covid-19 cases in the US this year as summer began. Both FLiRT and LB.1 are highly transmissible, as per a report by Indian Express.

What are the symptoms of LB.1?

LB.1 does not seem to be causing any distinct or new symptoms and there is no indication that it produces more severe disease, the experts emphasize.

The symptoms of LB.1 are very similar to those caused by the FLiRT variants, which include:

  • Sore throat
  • Cough
  • Fatigue
  • Congestion
  • Runny nose
  • Fever or chills
  • Headache
  • Muscle aches
  • New loss of sense of taste or smell
  • Nausea or vomiting
  • Diarrhea

The newer strains appear to be producing generally milder infections.

Transmission and Spread

How LB.1 Spreads

LB.1 spreads primarily through respiratory droplets when an infected person coughs, sneezes, or talks. It can also spread by touching surfaces contaminated with the virus and then touching the face.

Transmission Rates Compared to Other Variants

Early studies indicate that LB.1 might have a higher transmission rate than previous variants like Delta and Omicron. This makes it a cause for concern, especially in densely populated areas.

Impact on Different Age Groups

Vulnerability of Children

Children, especially those under 12 who are not yet eligible for vaccination in many countries, may be more susceptible to LB.1. Schools and daycare centers are critical areas for monitoring and implementing preventive measures.

Effects on Adults and the Elderly

Adults and the elderly, particularly those with underlying health conditions, are at higher risk of severe illness from LB.1. Vaccination significantly reduces this risk, but breakthrough infections can still occur.

Testing for the LB.1 Variant

Available Tests

PCR tests remain the gold standard for detecting COVID-19 and its variants. Some antigen tests can also detect the virus, but their accuracy may vary.

Accuracy of Testing Methods

Genomic sequencing is required to confirm the presence of the LB.1 variant specifically. While PCR tests can indicate infection, they do not differentiate between variants without further analysis.

Vaccines and the LB.1 Variant

Effectiveness of Existing Vaccines

Current vaccines provide a level of protection against LB.1, particularly against severe disease and hospitalization. However, their effectiveness might be slightly reduced compared to other variants.

Booster Shots and Future Vaccines

Booster shots are being recommended to enhance immunity against LB.1. Research is ongoing to develop updated vaccines that target this and other emerging variants more effectively.

Treatment Options

Current Treatments

Standard treatments for COVID-19, such as antiviral medications, corticosteroids, and supportive care, are being used for LB.1. The effectiveness of these treatments remains consistent.

Experimental Treatments

New treatments, including monoclonal antibodies tailored to LB.1, are under investigation. These experimental therapies aim to provide more targeted and effective options for those infected with this variant.

Where is LB.1 rising fastest?

In California, one of the states that saw trends of the virus rise earliest this summer in wastewater to “high” levels, the CDC’s COVID-NET data shows hospitalizations were near levels not seen there since February. 

More recent data from emergency rooms in California also shows rates of COVID-19 patients have risen to levels not seen since February.

But the KP.3 variant — not LB.1 — made up the largest proportion of cases during that early surge, estimates from the CDC as well as California’s health department suggest

Just 7.8% of cases in HHS Region 9, which spans California and some other western states, were projected to be from the LB.1 variant through June 8.

Instead, LB.1’s prevalence looks to be largest in HHS Region 2, which includes New York and New Jersey. Through June 8, 30.9% of cases are estimated to have been caused by LB.1.

What’s different about LB.1?

Compared to highly mutated SARS-CoV-2 variants that showed up earlier during the pandemic, experts say LB.1’s changes are relatively small compared to its parent variant JN.1, which was dominant during this past winter’s wave. 

LB.1 is also closely related to KP.3, which is also a descendant of the JN.1 variant. Unlike KP.3, LB.1 has a key mutation that scientists call S:S31del that looks to be helping it spread faster.

Research by scientists in Japan this month, which was released as a preprint that has not yet been peer reviewed, found that this mutation seemed to be more infectious and better at evading the immune system.

How to protect against LB.1 variant

As COVID-19 cases keep rising this summer, consider taking additional steps to protect yourself and others. The CDC recommends people:

  • Stay up to date with COVID-19 vaccines.
  • Wear a mask in crowded, indoor spaces.
  • Practice good hand hygiene.
  • Cover coughs and sneezes.
  • Improve ventilation.
  • Practice social distancing.

Conclusion

The LB.1 variant is the latest challenge in the ongoing battle against COVID-19. Understanding its characteristics, symptoms, and how it spreads is vital for protecting ourselves and our communities. By staying informed and following public health guidelines, we can navigate this new phase of the pandemic together.

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